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Description

This dual-hormone mechanism of action sets Mounjaro apart from Retatrutide, which primarily focuses on the GLP-1 hormone

Rhythm Pharma is modulating the MC4R and POMC pathways in rare genetic (congenital) forms of obesitythough this work may not translate beyond these populations

[DOI] [PubMed] [Google Scholar] 87

In line with the greater decrease in body weight and body fat mass in mice treated with GLP-1RA/tesaglitazar (Fig